The Adobe Flash plugin is needed to view this content. View and Download PowerPoint Presentations on Framingham Heart Study 2013 PPT. 10.1126/science.1142842.McPherson R, Pertsemlidis A, Kavaslar N, Stewart A, Roberts R, Cox DR, Hinds DA, Pennacchio LA, Tybjaerg-Hansen A, Folsom AR, Boerwinkle E, Hobbs HH, Cohen JC: A Common Allele on Chromosome 9 Associated with Coronary Heart Disease. 10.1111/j.1749-6632.1963.tb13299.x.Wadman M: Genome miners rush to stake claims. Arterioscler Thromb Vasc Biol. BMC Med Genet. MOP-version 1.0 . Such seminal findings as the effects of smoking and high cholesterol on heart … 2007, 316 (5830): 1488-1491. Cardiovascular disease (CVD) remains the leading cause of death in the U.S. population .Current guidelines recommend aggressive risk modifying treatment regimens in apparently healthy individuals deemed to be at high cardiovascular risk .These individuals can be identified using risk scores based on traditional risk factors as defined by the Framingham Heart Study , . BMC Med Genet. 1961, 55: 33-50.Kathiresan S, Manning AK, Demissie S, D'Agostino RB, Surti A, Guiducci C, Gianniny L, Burtt NP, Melander O, Orho-Melander M, Arnett D, Peloso GM, Ordovas JM, Cupples LA: A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. Ann Intern Med. Nature. It is among the longest running, most comprehensively characterized multi-generational studies in the world.
10.1038/nature04226.NCI-NHGRI Working Group on Replication in Association Studies: Replicating genotype-phenotype associations. Nature.
The original cohort (study group) included two-thirds of the adult population (more than 5,200 residents) of Framingham, with ages ranging from 30 to 62 years. 2007, 8 (Suppl 1): S5-10.1186/1471-2350-8-S1-S5.Meigs JB, Manning AK, Fox CS, Florez JC, Liu C-Y, Cupples LA, Dupuis J: Genome-wide Association with Diabetes-Related Traits in the Framingham Heart Study.
Our three-volume, first edition book is now available online through your Britannica Premium membership.\r\nThe Framingham study was designed to track health information on men and women who initially did not show signs of heart disease. BMC Med Genet. Our editors will review what you’ve submitted and determine whether to revise the article.\r\n Access the world’s original book of answers.
10.1161/01.ATV.0000222011.13026.25. Framingham Heart Study, long-term research project developed to identify risk factors of cardiovascular disease, the findings of which had far-reaching impacts on medicine. At the time of publication these were novel cardiovascular disease (CVD) risk factors, now they are the basis of treatment and prevention in the US. 2007, 316 (5830): 1491-1493. 2005, 437: 1299-1320. Circulation Jan 2009 Diseases of The Heart Charles K Friedberg MD, WB Saunders Co. Philadelphia, 1949 Risk of Cardiovascular Events in Diabetics Framingham Study Risk of Coronary Heart Disease by Diabetic Status According to Level of Risk Factors Framingham Study Wilson PWF, Kannel WB. 2007, 8 (Suppl 1): S16-10.1186/1471-2350-8-S1-S16.Dawber TR, Kannel WB, Lyell LP: An approach to longitudinal studies in a community: the Framingham Study. 2007, 8 (Suppl 1): S18-10.1186/1471-2350-8-S1-S18.Dawber TR, Kannel WB, Revotskie N, Stokes JI, Kagan A, Gordon T: Some factors associated with the development of coronary heart disease; six years' follow-up experience in the Framingham Study. Indeed, much common knowledge about heart disease—including the effects of smoking, diet, and exercise—can be traced to the Framingham study. Is the Framingham study now on it's way to becoming the gold standard for genetic epidemiology of CVD? Remove this presentation Flag as Inappropriate I … The Framingham Heart Study, founded in 1948 to examine the epidemiology of cardiovascular disease in a small town outside of Boston, has become the worldwide standard for cardiovascular epidemiology. This Framingham risk score calculator estimates the 10-year coronary heart disease risk of any person based on certain criteria like gender, age, cholesterol and systolic pressure.
1963, 107: 539-556.
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